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considering that the glycolysis segment glycerol-3-phosphate 1,3-bisphosphoglycerate 3-phosphoglycerate (and downstream until phosphoenolpyruvate) is also reversible, interruption of the glycolytic pathway at the level of ALDO and/or above can be bypassed by provision of serine and glycine

Although their activity on a single target may be lower compared to single-target drugs, the synergistic effects of multi-target modulation result in a total effect greater than the sum of the individual effects, leading to better efficacy and fewer adverse reactions

The electrochemical sensor electrode was placed in the mixture, and the reference electrode and counter electrode were added at the same time

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